It is a well-ascertained fact, that in the cardiac[1] disease the only resource is wine. According to some authorities, however, wine should only be given when the attacks come on, while others, again, are of opinion, that it must only be administered between the attacks; it being the object with the former to arrest the profuse perspirations, while the latter base their practice on an impression that it may be given with more safety at a moment when the malady has diminished in intensity; and this I find is the opinion entertained by most people. In all cases, wine must only be administered just after taking food, never after sleep, and under no circumstances after any other kind of drink, or in other words, only when the patient is thirsty; in no case whatever should it be given, except at the very last extremity. Wine is better suited to males than to females, to aged people than to youths, to youths than to children, and to persons who are used to it than to those who are not in the habit of taking it; winter, too, is a better time for using it than summer. As to the quantity to be prescribed, and the proportion of water to be mixed with it, that depends entirely upon the strength of the wine; it is generally thought, however, that the best proportions are one cyathus of wine and two of water. If, however, there is a derangement of the stomach, and if the food does not pass downward, the wine must be given in a larger proportion.